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Effects of the COVID-19 pandemic on semen quality in male partners of infertile couples: a hospital-based observational study

The effects of the coronavirus disease 2019 (COVID-19) pandemic on male fertility have received considerable attention because human testes contain high levels of angiotensin-converting enzyme-2 receptors, through which severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can enter. Early st...

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Autores principales: Kumar, Tribhuwan, Jha, Kamlesh, Zabihullah, Md, Neelu, Kumari, Kumar, Yogesh, Siddharth, Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069688/
https://www.ncbi.nlm.nih.gov/pubmed/36348579
http://dx.doi.org/10.4103/aja202278
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author Kumar, Tribhuwan
Jha, Kamlesh
Zabihullah, Md
Neelu, Kumari
Kumar, Yogesh
Siddharth, Kumar
author_facet Kumar, Tribhuwan
Jha, Kamlesh
Zabihullah, Md
Neelu, Kumari
Kumar, Yogesh
Siddharth, Kumar
author_sort Kumar, Tribhuwan
collection PubMed
description The effects of the coronavirus disease 2019 (COVID-19) pandemic on male fertility have received considerable attention because human testes contain high levels of angiotensin-converting enzyme-2 receptors, through which severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can enter. Early studies showed decreases in semen quality during and after recovery from COVID-19. However, no semen quality studies have examined the effects of widespread subclinical and mild disease, as well as changes in lifestyle, psychosocial behavior, intake of dietary supplements, and stress. This cross-sectional study compared semen quality parameters in male partners of infertile couples between men who underwent semen analysis before the COVID-19 pandemic (prepandemic group) and men who underwent semen analysis during the pandemic period (pandemic group); the analysis sought to clarify the overall effects of the pandemic. No participants in the pandemic group had experienced clinically overt disease. Among the 239 participants, mean body weight (P = 0.001), mean body mass index (P < 0.001), median sperm concentration (P = 0.014), total sperm count (P = 0.006), and total percentages of motile (P = 0.013) and abnormal cells (P < 0.001) were significantly greater in the pandemic group (n = 137) than those in the prepandemic group (n = 102). Among abnormal cells, the percentages of cells with excess residual cytoplasm (P < 0.001), head defects (P < 0.001), and tail defects (P = 0.015) were significantly greater in the pandemic group than those in the prepandemic group. With the exception of morphology, the overall semenogram results were better in the pandemic group than those in the prepandemic group.
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spelling pubmed-100696882023-04-04 Effects of the COVID-19 pandemic on semen quality in male partners of infertile couples: a hospital-based observational study Kumar, Tribhuwan Jha, Kamlesh Zabihullah, Md Neelu, Kumari Kumar, Yogesh Siddharth, Kumar Asian J Androl Original Article The effects of the coronavirus disease 2019 (COVID-19) pandemic on male fertility have received considerable attention because human testes contain high levels of angiotensin-converting enzyme-2 receptors, through which severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can enter. Early studies showed decreases in semen quality during and after recovery from COVID-19. However, no semen quality studies have examined the effects of widespread subclinical and mild disease, as well as changes in lifestyle, psychosocial behavior, intake of dietary supplements, and stress. This cross-sectional study compared semen quality parameters in male partners of infertile couples between men who underwent semen analysis before the COVID-19 pandemic (prepandemic group) and men who underwent semen analysis during the pandemic period (pandemic group); the analysis sought to clarify the overall effects of the pandemic. No participants in the pandemic group had experienced clinically overt disease. Among the 239 participants, mean body weight (P = 0.001), mean body mass index (P < 0.001), median sperm concentration (P = 0.014), total sperm count (P = 0.006), and total percentages of motile (P = 0.013) and abnormal cells (P < 0.001) were significantly greater in the pandemic group (n = 137) than those in the prepandemic group (n = 102). Among abnormal cells, the percentages of cells with excess residual cytoplasm (P < 0.001), head defects (P < 0.001), and tail defects (P = 0.015) were significantly greater in the pandemic group than those in the prepandemic group. With the exception of morphology, the overall semenogram results were better in the pandemic group than those in the prepandemic group. Wolters Kluwer - Medknow 2022-11-01 /pmc/articles/PMC10069688/ /pubmed/36348579 http://dx.doi.org/10.4103/aja202278 Text en Copyright: © The Author(s)(2022) https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Kumar, Tribhuwan
Jha, Kamlesh
Zabihullah, Md
Neelu, Kumari
Kumar, Yogesh
Siddharth, Kumar
Effects of the COVID-19 pandemic on semen quality in male partners of infertile couples: a hospital-based observational study
title Effects of the COVID-19 pandemic on semen quality in male partners of infertile couples: a hospital-based observational study
title_full Effects of the COVID-19 pandemic on semen quality in male partners of infertile couples: a hospital-based observational study
title_fullStr Effects of the COVID-19 pandemic on semen quality in male partners of infertile couples: a hospital-based observational study
title_full_unstemmed Effects of the COVID-19 pandemic on semen quality in male partners of infertile couples: a hospital-based observational study
title_short Effects of the COVID-19 pandemic on semen quality in male partners of infertile couples: a hospital-based observational study
title_sort effects of the covid-19 pandemic on semen quality in male partners of infertile couples: a hospital-based observational study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069688/
https://www.ncbi.nlm.nih.gov/pubmed/36348579
http://dx.doi.org/10.4103/aja202278
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