Cargando…

The value of discharged case fatality rate in estimating the severity and epidemic trend of COVID-19 in China: a novel epidemiological study

AIM: The main objective of this study was to explore the value of the discharged case fatality rate (DCFR) in estimating the severity and epidemic trend of COVID-19 in China. SUBJECTS AND METHODS: Epidemiological data on COVID-19 in China and Hubei Province were obtained from the National Health Com...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Kexuan, Guo, Zhifeng, Yan, Mengqing, Fan, Yahui, Liu, Xiaohua, Yang, Yongli, Gao, Fuxiao, Xie, Fangli, Wang, Peizhong Peter, Yao, Wu, Wang, Qi, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069734/
https://www.ncbi.nlm.nih.gov/pubmed/37361283
http://dx.doi.org/10.1007/s10389-023-01895-4
_version_ 1785018906671316992
author Cheng, Kexuan
Guo, Zhifeng
Yan, Mengqing
Fan, Yahui
Liu, Xiaohua
Yang, Yongli
Gao, Fuxiao
Xie, Fangli
Wang, Peizhong Peter
Yao, Wu
Wang, Qi
Wang, Wei
author_facet Cheng, Kexuan
Guo, Zhifeng
Yan, Mengqing
Fan, Yahui
Liu, Xiaohua
Yang, Yongli
Gao, Fuxiao
Xie, Fangli
Wang, Peizhong Peter
Yao, Wu
Wang, Qi
Wang, Wei
author_sort Cheng, Kexuan
collection PubMed
description AIM: The main objective of this study was to explore the value of the discharged case fatality rate (DCFR) in estimating the severity and epidemic trend of COVID-19 in China. SUBJECTS AND METHODS: Epidemiological data on COVID-19 in China and Hubei Province were obtained from the National Health Commission of the People’s Republic of China from January 20, 2020, to March 31, 2020. The number of daily new confirmed cases, daily confirmed deaths, daily recovered cases, the proportion of daily deaths and total deaths of discharged cases were collected, and the total discharge case fatality rate (tDCFR), daily discharge case fatality rate (dDCFR), and stage-discharge case fatality rate (sDCFR) were calculated. We used the R software (version 3.6.3, R core team) to apply a trimmed exact linear time method to search for changes in the mean and variance of dDCFR in order to estimate the pandemic phase from dDCFR. RESULTS: The tDCFR of COVID-19 in China was 4.16% until March 31, 2020. According to the pattern of dDCFR, the pandemic was divided into four phases: the transmission phase (from January 20 to February 2), the epidemic phase (from February 3 to February 14), the decline phase (from February 15 to February 22), and the sporadic phase (from February 23 to March 31). The sDCFR for these four phases was 43.18% (CI 39.82–46.54%), 13.23% (CI 12.52–13.94%), 5.86% (CI 5.49–6.22%), and 1.61% (CI 1.50–1.72%), respectively. CONCLUSION: DCFR has great value in assessing the severity and epidemic trend of COVID-19. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10389-023-01895-4.
format Online
Article
Text
id pubmed-10069734
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Springer Berlin Heidelberg
record_format MEDLINE/PubMed
spelling pubmed-100697342023-04-04 The value of discharged case fatality rate in estimating the severity and epidemic trend of COVID-19 in China: a novel epidemiological study Cheng, Kexuan Guo, Zhifeng Yan, Mengqing Fan, Yahui Liu, Xiaohua Yang, Yongli Gao, Fuxiao Xie, Fangli Wang, Peizhong Peter Yao, Wu Wang, Qi Wang, Wei Z Gesundh Wiss Original Article AIM: The main objective of this study was to explore the value of the discharged case fatality rate (DCFR) in estimating the severity and epidemic trend of COVID-19 in China. SUBJECTS AND METHODS: Epidemiological data on COVID-19 in China and Hubei Province were obtained from the National Health Commission of the People’s Republic of China from January 20, 2020, to March 31, 2020. The number of daily new confirmed cases, daily confirmed deaths, daily recovered cases, the proportion of daily deaths and total deaths of discharged cases were collected, and the total discharge case fatality rate (tDCFR), daily discharge case fatality rate (dDCFR), and stage-discharge case fatality rate (sDCFR) were calculated. We used the R software (version 3.6.3, R core team) to apply a trimmed exact linear time method to search for changes in the mean and variance of dDCFR in order to estimate the pandemic phase from dDCFR. RESULTS: The tDCFR of COVID-19 in China was 4.16% until March 31, 2020. According to the pattern of dDCFR, the pandemic was divided into four phases: the transmission phase (from January 20 to February 2), the epidemic phase (from February 3 to February 14), the decline phase (from February 15 to February 22), and the sporadic phase (from February 23 to March 31). The sDCFR for these four phases was 43.18% (CI 39.82–46.54%), 13.23% (CI 12.52–13.94%), 5.86% (CI 5.49–6.22%), and 1.61% (CI 1.50–1.72%), respectively. CONCLUSION: DCFR has great value in assessing the severity and epidemic trend of COVID-19. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10389-023-01895-4. Springer Berlin Heidelberg 2023-04-03 /pmc/articles/PMC10069734/ /pubmed/37361283 http://dx.doi.org/10.1007/s10389-023-01895-4 Text en © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Article
Cheng, Kexuan
Guo, Zhifeng
Yan, Mengqing
Fan, Yahui
Liu, Xiaohua
Yang, Yongli
Gao, Fuxiao
Xie, Fangli
Wang, Peizhong Peter
Yao, Wu
Wang, Qi
Wang, Wei
The value of discharged case fatality rate in estimating the severity and epidemic trend of COVID-19 in China: a novel epidemiological study
title The value of discharged case fatality rate in estimating the severity and epidemic trend of COVID-19 in China: a novel epidemiological study
title_full The value of discharged case fatality rate in estimating the severity and epidemic trend of COVID-19 in China: a novel epidemiological study
title_fullStr The value of discharged case fatality rate in estimating the severity and epidemic trend of COVID-19 in China: a novel epidemiological study
title_full_unstemmed The value of discharged case fatality rate in estimating the severity and epidemic trend of COVID-19 in China: a novel epidemiological study
title_short The value of discharged case fatality rate in estimating the severity and epidemic trend of COVID-19 in China: a novel epidemiological study
title_sort value of discharged case fatality rate in estimating the severity and epidemic trend of covid-19 in china: a novel epidemiological study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069734/
https://www.ncbi.nlm.nih.gov/pubmed/37361283
http://dx.doi.org/10.1007/s10389-023-01895-4
work_keys_str_mv AT chengkexuan thevalueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT guozhifeng thevalueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT yanmengqing thevalueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT fanyahui thevalueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT liuxiaohua thevalueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT yangyongli thevalueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT gaofuxiao thevalueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT xiefangli thevalueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT wangpeizhongpeter thevalueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT yaowu thevalueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT wangqi thevalueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT wangwei thevalueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT chengkexuan valueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT guozhifeng valueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT yanmengqing valueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT fanyahui valueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT liuxiaohua valueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT yangyongli valueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT gaofuxiao valueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT xiefangli valueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT wangpeizhongpeter valueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT yaowu valueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT wangqi valueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy
AT wangwei valueofdischargedcasefatalityrateinestimatingtheseverityandepidemictrendofcovid19inchinaanovelepidemiologicalstudy