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Effect of an aqueous 4% titanium tetrafluoride solution on preventing caries in orthodontic patients: a controlled clinical trial

INTRODUCTION: Titanium tetrafluoride (TiF(4)) is a fluoride compound that, when is applied over enamel, promotes a protection against demineralization through a titanium dioxide (TiO(2)) acid-resistant coat. OBJECTIVES: This study sought to verify the hypothesis that a single application of 4% TiF(4...

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Autores principales: CHEVITARESE, Ana Beatriz, LEITE, Karla Lorene de França, DUTRA, Paulo Bechara, PITHON, Matheus Melo, FARIA, Lucianne Cople Maia, RUELLAS, Antônio Carlos de Oliveira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dental Press International 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069748/
https://www.ncbi.nlm.nih.gov/pubmed/37018831
http://dx.doi.org/10.1590/2177-6709.28.1.e2321304.oar
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author CHEVITARESE, Ana Beatriz
LEITE, Karla Lorene de França
DUTRA, Paulo Bechara
PITHON, Matheus Melo
FARIA, Lucianne Cople Maia
RUELLAS, Antônio Carlos de Oliveira
author_facet CHEVITARESE, Ana Beatriz
LEITE, Karla Lorene de França
DUTRA, Paulo Bechara
PITHON, Matheus Melo
FARIA, Lucianne Cople Maia
RUELLAS, Antônio Carlos de Oliveira
author_sort CHEVITARESE, Ana Beatriz
collection PubMed
description INTRODUCTION: Titanium tetrafluoride (TiF(4)) is a fluoride compound that, when is applied over enamel, promotes a protection against demineralization through a titanium dioxide (TiO(2)) acid-resistant coat. OBJECTIVES: This study sought to verify the hypothesis that a single application of 4% TiF(4) increases the resistance of enamel to dental demineralization in orthodontic patients. MATERIALS AND METHODS: This controlled clinical trial followed CONSORT guidelines and investigated the prevention of enamel demineralization, fluoride retention, and the presence of a Ti layer after TiF(4) application on banded teeth exposed to clinical cariogenic biofilm. Forty premolars were divided into a control group (CG; n = 20) and a test group (TG; n = 20). Teeth from both groups received prophylaxis and orthodontic bands with a cariogenic locus. In the TG, all teeth additionally underwent aqueous 4% TiF(4) solution application after prophylaxis before being banded. After one month, teeth from both groups were extracted and prepared to assess the microhardness, fluoride retention, and evaluation of the Ti coating over the enamel surface. All data were analyzed with a paired Student’s t-test (p<0.05). RESULTS: Enamel microhardness and fluoride uptake were higher in TG than in CG, while the Ti layer could be seen over TG teeth that received TiF(4) application. CONCLUSION: Under clinical circumstances, the 4% aqueous TiF(4) solution was effective in preventing enamel mineral loss through increasing the enamel resistance to dental demineralization, enhancing its microhardness and fluoride uptake, and forming a Ti coat.
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spelling pubmed-100697482023-04-04 Effect of an aqueous 4% titanium tetrafluoride solution on preventing caries in orthodontic patients: a controlled clinical trial CHEVITARESE, Ana Beatriz LEITE, Karla Lorene de França DUTRA, Paulo Bechara PITHON, Matheus Melo FARIA, Lucianne Cople Maia RUELLAS, Antônio Carlos de Oliveira Dental Press J Orthod Original Article INTRODUCTION: Titanium tetrafluoride (TiF(4)) is a fluoride compound that, when is applied over enamel, promotes a protection against demineralization through a titanium dioxide (TiO(2)) acid-resistant coat. OBJECTIVES: This study sought to verify the hypothesis that a single application of 4% TiF(4) increases the resistance of enamel to dental demineralization in orthodontic patients. MATERIALS AND METHODS: This controlled clinical trial followed CONSORT guidelines and investigated the prevention of enamel demineralization, fluoride retention, and the presence of a Ti layer after TiF(4) application on banded teeth exposed to clinical cariogenic biofilm. Forty premolars were divided into a control group (CG; n = 20) and a test group (TG; n = 20). Teeth from both groups received prophylaxis and orthodontic bands with a cariogenic locus. In the TG, all teeth additionally underwent aqueous 4% TiF(4) solution application after prophylaxis before being banded. After one month, teeth from both groups were extracted and prepared to assess the microhardness, fluoride retention, and evaluation of the Ti coating over the enamel surface. All data were analyzed with a paired Student’s t-test (p<0.05). RESULTS: Enamel microhardness and fluoride uptake were higher in TG than in CG, while the Ti layer could be seen over TG teeth that received TiF(4) application. CONCLUSION: Under clinical circumstances, the 4% aqueous TiF(4) solution was effective in preventing enamel mineral loss through increasing the enamel resistance to dental demineralization, enhancing its microhardness and fluoride uptake, and forming a Ti coat. Dental Press International 2023-04-03 /pmc/articles/PMC10069748/ /pubmed/37018831 http://dx.doi.org/10.1590/2177-6709.28.1.e2321304.oar Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Original Article
CHEVITARESE, Ana Beatriz
LEITE, Karla Lorene de França
DUTRA, Paulo Bechara
PITHON, Matheus Melo
FARIA, Lucianne Cople Maia
RUELLAS, Antônio Carlos de Oliveira
Effect of an aqueous 4% titanium tetrafluoride solution on preventing caries in orthodontic patients: a controlled clinical trial
title Effect of an aqueous 4% titanium tetrafluoride solution on preventing caries in orthodontic patients: a controlled clinical trial
title_full Effect of an aqueous 4% titanium tetrafluoride solution on preventing caries in orthodontic patients: a controlled clinical trial
title_fullStr Effect of an aqueous 4% titanium tetrafluoride solution on preventing caries in orthodontic patients: a controlled clinical trial
title_full_unstemmed Effect of an aqueous 4% titanium tetrafluoride solution on preventing caries in orthodontic patients: a controlled clinical trial
title_short Effect of an aqueous 4% titanium tetrafluoride solution on preventing caries in orthodontic patients: a controlled clinical trial
title_sort effect of an aqueous 4% titanium tetrafluoride solution on preventing caries in orthodontic patients: a controlled clinical trial
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069748/
https://www.ncbi.nlm.nih.gov/pubmed/37018831
http://dx.doi.org/10.1590/2177-6709.28.1.e2321304.oar
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