Brief Report: Suboptimal Lopinavir Exposure in Infants on Rifampicin Treatment Receiving Double-dosed or Semisuperboosted Lopinavir/Ritonavir: Time for a Change

Although super-boosted lopinavir/ritonavir (LPV/r; ratio 4:4 instead of 4:1) is recommended for infants living with HIV and receiving concomitant rifampicin, in clinical practice, many different LPV/r dosing strategies are applied due to poor availability of pediatric separate ritonavir formulations...

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Detalles Bibliográficos
Autores principales: Jacobs, Tom G., Mumbiro, Vivian, Chitsamatanga, Moses, Namuziya, Natasha, Passanduca, Alfeu, Domínguez-Rodríguez, Sara, Tagarro, Alfredo, Nathoo, Kusum J., Nduna, Bwendo, Ballesteros, Alvaro, Madrid, Lola, Mujuru, Hilda A., Chabala, Chishala, Buck, W. Chris, Rojo, Pablo, Burger, David M., Moraleda, Cinta, Colbers, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAIDS Journal of Acquired Immune Deficiency Syndromes 2023
Materias:
Clinical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069754/
https://www.ncbi.nlm.nih.gov/pubmed/36724434
http://dx.doi.org/10.1097/QAI.0000000000003168

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