Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion

Pancreatic ductal adenocarcinoma (PDAC) continues to show no improvement in survival rates. One aspect of PDAC is elevated ATP levels, pointing to the purinergic axis as a potential attractive therapeutic target. Mediated in part by highly druggable extracellular proteins, this axis plays essential...

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Detalles Bibliográficos
Autores principales: Tomas Bort, Elena, Joseph, Megan D, Wang, Qiaoying, Carter, Edward P, Roth, Nicolas J, Gibson, Jessica, Samadi, Ariana, Kocher, Hemant M, Simoncelli, Sabrina, McCormick, Peter J, Grose, Richard P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069867/
https://www.ncbi.nlm.nih.gov/pubmed/36942939
http://dx.doi.org/10.7554/eLife.86971

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