Cargando…
Lineage-specific differences and regulatory networks governing human chondrocyte development
To address large gaps in our understanding of the molecular regulation of articular and growth plate cartilage development in humans, we used our directed differentiation approach to generate these distinct cartilage tissues from human embryonic stem cells. The resulting transcriptomic profiles of h...
Autores principales: | Richard, Daniel, Pregizer, Steven, Venkatasubramanian, Divya, Raftery, Rosanne M, Muthuirulan, Pushpanathan, Liu, Zun, Capellini, Terence D, Craft, April M |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069868/ https://www.ncbi.nlm.nih.gov/pubmed/36920035 http://dx.doi.org/10.7554/eLife.79925 |
Ejemplares similares
-
Epigenetic profiling of growth plate chondrocytes sheds insight into regulatory genetic variation influencing height
por: Guo, Michael, et al.
Publicado: (2017) -
Joint disease-specificity at the regulatory base-pair level
por: Muthuirulan, Pushpanathan, et al.
Publicado: (2021) -
Author Correction: Joint disease-specificity at the regulatory base-pair level
por: Muthuirulan, Pushpanathan, et al.
Publicado: (2022) -
Calreticulin regulates a switch between osteoblast and chondrocyte lineages derived from murine embryonic stem cells
por: Pilquil, Carlos, et al.
Publicado: (2020) -
MMP14 cleaves PTH1R in the chondrocyte-derived osteoblast lineage, curbing signaling intensity for proper bone anabolism
por: Chu, Tsz Long, et al.
Publicado: (2023)