Human IL-23 is essential for IFN-γ-dependent immunity to mycobacteria

Patients with autosomal recessive (AR) IL-12p40 or IL-12Rβ1 deficiency display Mendelian susceptibility to mycobacterial disease (MSMD) due to impaired IFN-γ production and, less commonly, chronic mucocutaneous candidiasis (CMC) due to impaired IL-17A/F production. We report six patients from four k...

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Detalles Bibliográficos
Autores principales: Philippot, Quentin, Ogishi, Masato, Bohlen, Jonathan, Puchan, Julia, Arias, Andrés Augusto, Nguyen, Tina, Martin-Fernandez, Marta, Conil, Clement, Rinchai, Darawan, Momenilandi, Mana, Mahdaviani, Alireza, Keramatipour, Mohammad, Rosain, Jérémie, Yang, Rui, Khan, Taushif, Neehus, Anna-Lena, Materna, Marie, Han, Ji Eun, Peel, Jessica, Mele, Federico, Weisshaar, Marc, Jovic, Sandra, Bastard, Paul, Lévy, Romain, Le Voyer, Tom, Zhang, Peng, Renkilaraj, Majistor Raj Luxman Maglorius, Arango-Franco, Carlos A., Pelham, Simon, Seeleuthner, Yoann, Pochon, Mathieu, Ata, Manar Mahmoud Ahmad, Ali, Fatima Al, Migaud, Mélanie, Soudée, Camille, Kochetkov, Tatiana, Molitor, Anne, Carapito, Raphael, Bahram, Seiamak, Boisson, Bertrand, Fieschi, Claire, Mansouri, Davood, Marr, Nico, Okada, Satoshi, Shahrooei, Mohammad, Parvaneh, Nima, Chavoshzadeh, Zahra, Cobat, Aurélie, Bogunovic, Dusan, Abel, Laurent, Tangye, Stuart, Ma, Cindy S., Béziat, Vivien, Sallusto, Federica, Boisson-Dupuis, Stéphanie, Bustamante, Jacinta, Casanova, Jean-Laurent, Puel, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069949/
https://www.ncbi.nlm.nih.gov/pubmed/36763636
http://dx.doi.org/10.1126/sciimmunol.abq5204

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