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The link between chronic cocaine use, B cell perturbations, and blunted immune recovery in HIV-infected individuals on suppressive ART

BACKGROUND: We recently reveal that anti-CD4 autoantibodies contribute to blunted CD4+ T cell reconstitution in HIV+ individuals on antiretroviral therapy (ART). Cocaine use is common among HIV+ individuals and is associated with accelerated disease progression. However, the mechanisms underlying co...

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Detalles Bibliográficos
Autores principales: Cheng, Da, Luo, Zhenwu, Fitting, Sylvia, Stoops, William, Heath, Sonya L., Ndhlovu, Lishomwa C., Jiang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070012/
https://www.ncbi.nlm.nih.gov/pubmed/37027536
http://dx.doi.org/10.1515/nipt-2022-0019

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