Cargando…
The link between chronic cocaine use, B cell perturbations, and blunted immune recovery in HIV-infected individuals on suppressive ART
BACKGROUND: We recently reveal that anti-CD4 autoantibodies contribute to blunted CD4+ T cell reconstitution in HIV+ individuals on antiretroviral therapy (ART). Cocaine use is common among HIV+ individuals and is associated with accelerated disease progression. However, the mechanisms underlying co...
Autores principales: | Cheng, Da, Luo, Zhenwu, Fitting, Sylvia, Stoops, William, Heath, Sonya L., Ndhlovu, Lishomwa C., Jiang, Wei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070012/ https://www.ncbi.nlm.nih.gov/pubmed/37027536 http://dx.doi.org/10.1515/nipt-2022-0019 |
Ejemplares similares
-
HIV viral transcription and immune perturbations in the CNS of people with HIV despite ART
por: Farhadian, Shelli F., et al.
Publicado: (2022) -
Impacts of plasma microbial lipopolysaccharide translocation on B cell perturbations and anti-CD4 autoantibody production in people with HIV on suppressive antiretroviral therapy
por: Fu, Xiaoyu, et al.
Publicado: (2023) -
Cocaine perturbs mitovesicle biology in the brain
por: D'Acunzo, Pasquale, et al.
Publicado: (2023) -
Activation Associated ERK1/2 Signaling Impairments in CD8(+) T Cells Co-Localize with Blunted Polyclonal and HIV-1 Specific Effector Functions in Early Untreated HIV-1 Infection
por: Crawford, Timothy Q., et al.
Publicado: (2013) -
Increased Natural Killer Cell Activation in HIV-Infected Immunologic Non-Responders Correlates with CD4+ T Cell Recovery after Antiretroviral Therapy and Viral Suppression
por: Luo, Zhenwu, et al.
Publicado: (2017)