PPAR-γ Activation Alleviates Osteoarthritis through Both the Nrf2/NLRP3 and PGC-1α/Δψ(m) Pathways by Inhibiting Pyroptosis

Osteoarthritis (OA) is a common degenerative joint disease with a gradually increasing morbidity in the aging and obese population. Emerging evidence has implicated pyroptosis in the etiology of OA and it may be recognized as a therapeutic target in OA. We have previously reported regarding another...

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Detalles Bibliográficos
Autores principales: Feng, Zhencheng, Huang, Qiuxiang, Zhang, Xingliang, Xu, Pengfei, Li, Siming, Ma, Dongli, Meng, Qingqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070030/
https://www.ncbi.nlm.nih.gov/pubmed/37020714
http://dx.doi.org/10.1155/2023/2523536

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