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The m(6)A methyltransferase METTL16 negatively regulates MCP1 expression in mesenchymal stem cells during monocyte recruitment

Mesenchymal stem cells (MSCs) possess strong immunoregulatory functions, one aspect of which is recruiting monocytes from peripheral vessels to local tissue by secreting monocyte chemoattractant protein 1 (MCP1). However, the regulatory mechanisms of MCP1 secretion in MSCs are still unclear. Recentl...

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Detalles Bibliográficos
Autores principales: Zhang, Zhaoqiang, Xie, Zhongyu, Lin, Jiajie, Sun, Zehang, Li, Zhikun, Yu, Wenhui, Zeng, Yipeng, Ye, Guiwen, Li, Jinteng, Ye, Feng, Su, Zepeng, Che, Yunshu, Xu, Peitao, Zeng, Chenying, Wang, Peng, Wu, Yanfeng, Shen, Huiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070103/
https://www.ncbi.nlm.nih.gov/pubmed/36795489
http://dx.doi.org/10.1172/jci.insight.162436