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The m(6)A methyltransferase METTL16 negatively regulates MCP1 expression in mesenchymal stem cells during monocyte recruitment
Mesenchymal stem cells (MSCs) possess strong immunoregulatory functions, one aspect of which is recruiting monocytes from peripheral vessels to local tissue by secreting monocyte chemoattractant protein 1 (MCP1). However, the regulatory mechanisms of MCP1 secretion in MSCs are still unclear. Recentl...
Autores principales: | Zhang, Zhaoqiang, Xie, Zhongyu, Lin, Jiajie, Sun, Zehang, Li, Zhikun, Yu, Wenhui, Zeng, Yipeng, Ye, Guiwen, Li, Jinteng, Ye, Feng, Su, Zepeng, Che, Yunshu, Xu, Peitao, Zeng, Chenying, Wang, Peng, Wu, Yanfeng, Shen, Huiyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070103/ https://www.ncbi.nlm.nih.gov/pubmed/36795489 http://dx.doi.org/10.1172/jci.insight.162436 |
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