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CC16 augmentation reduces exaggerated COPD-like disease in Cc16-deficient mice

Low Club Cell 16 kDa protein (CC16) plasma levels are linked to accelerated lung function decline in patients with chronic obstructive pulmonary disease (COPD). Cigarette smoke–exposed (CS-exposed) Cc16(–/–) mice have exaggerated COPD-like disease associated with increased NF-κB activation in their...

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Detalles Bibliográficos
Autores principales:	Rojas-Quintero, Joselyn, Laucho-Contreras, Maria Eugenia, Wang, Xiaoyun, Fucci, Quynh-Anh, Burkett, Patrick R., Kim, Se-Jin, Zhang, Duo, Tesfaigzi, Yohannes, Li, Yuhong, Bhashyam, Abhiram R., Li, Zhang, Khamas, Haider, Celli, Bartolome, Pilon, Aprile L., Polverino, Francesca, Owen, Caroline A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070105/ https://www.ncbi.nlm.nih.gov/pubmed/36787195 http://dx.doi.org/10.1172/jci.insight.130771

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