Sorting nexin 10 sustains PDGF receptor signaling in glioblastoma stem cells via endosomal protein sorting

Glioblastoma is the most malignant primary brain tumor, the prognosis of which remains dismal even with aggressive surgical, medical, and radiation therapies. Glioblastoma stem cells (GSCs) promote therapeutic resistance and cellular heterogeneity due to their self-renewal properties and capacity fo...

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Detalles Bibliográficos
Autores principales: Gimple, Ryan C., Zhang, Guoxin, Wang, Shuai, Huang, Tengfei, Lee, Jina, Taori, Suchet, Lv, Deguan, Dixit, Deobrat, Halbert, Matthew E., Morton, Andrew R., Kidwell, Reilly L., Dong, Zhen, Prager, Briana C., Kim, Leo J.Y., Qiu, Zhixin, Zhao, Linjie, Xie, Qi, Wu, Qiulian, Agnihotri, Sameer, Rich, Jeremy N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070110/
https://www.ncbi.nlm.nih.gov/pubmed/36795488
http://dx.doi.org/10.1172/jci.insight.158077

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