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IL-13RA2 downregulation in fibroblasts promotes keloid fibrosis via JAK/STAT6 activation
Keloids are considered the manifestation of a fibroproliferative disease characterized by chronic inflammation that is induced following skin injury. Deciphering the underlying mechanism of keloid formation is essential for improving treatment outcomes. Here, we found that more macrophages were acti...
Autores principales: | Chao, Hua, Zheng, Lisheng, Hsu, Pojui, He, Jinyun, Wu, Ridong, Xu, Shuqia, Zeng, Ruixi, Zhou, Yuan, Ma, Huisi, Liu, Haibo, Tang, Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070111/ https://www.ncbi.nlm.nih.gov/pubmed/36757802 http://dx.doi.org/10.1172/jci.insight.157091 |
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