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Transcription factor c-Maf deletion improves streptozotocin-induced diabetic nephropathy by directly regulating Sglt2 and Glut2

The transcription factor c-Maf has been widely studied and has been reported to play a critical role in embryonic kidney development; however, the postnatal functions of c-Maf in adult kidneys remain unknown as c-Maf–null C57BL/6J mice exhibit embryonic lethality. In this study, we investigated the...

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Detalles Bibliográficos
Autores principales: Fujino, Mitsunori, Morito, Naoki, Hayashi, Takuto, Ojima, Masami, Ishibashi, Shun, Kuno, Akihiro, Koshiba, Seizo, Yamagata, Kunihiro, Takahashi, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070115/
https://www.ncbi.nlm.nih.gov/pubmed/36787192
http://dx.doi.org/10.1172/jci.insight.163306