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Tumour-educated platelets for breast cancer detection: biological and technical insights

BACKGROUND: Studies have shown that blood platelets contain tumour-specific mRNA profiles tumour-educated platelets (TEPs). Here, we aim to train a TEP-based breast cancer detection classifier. METHODS: Platelet mRNA was sequenced from 266 women with stage I–IV breast cancer and 212 female controls...

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Detalles Bibliográficos
Autores principales: Liefaard, Marte C., Moore, Kat S., Mulder, Lennart, van den Broek, Daan, Wesseling, Jelle, Sonke, Gabe S., Wessels, Lodewyk F. A., Rookus, Matti, Lips, Esther H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070267/
https://www.ncbi.nlm.nih.gov/pubmed/36765174
http://dx.doi.org/10.1038/s41416-023-02174-5

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