Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans

The gut microbiota impacts systemic levels of multiple metabolites including NAD(+) precursors through diverse pathways. Nicotinamide riboside (NR) is an NAD(+) precursor capable of regulating mammalian cellular metabolism. Some bacterial families express the NR-specific transporter, PnuC. We hypoth...

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Detalles Bibliográficos
Autores principales: Peluso, A. Augusto, Lundgaard, Agnete T., Babaei, Parizad, Mousovich-Neto, Felippe, Rocha, Andréa L., Damgaard, Mads V., Bak, Emilie G., Gnanasekaran, Thiyagarajan, Dollerup, Ole L., Trammell, Samuel A. J., Nielsen, Thomas S., Kern, Timo, Abild, Caroline B., Sulek, Karolina, Ma, Tao, Gerhart-Hines, Zach, Gillum, Matthew P., Arumugam, Manimozhiyan, Ørskov, Cathrine, McCloskey, Douglas, Jessen, Niels, Herrgård, Markus J., Mori, Marcelo A. S., Treebak, Jonas T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070358/
https://www.ncbi.nlm.nih.gov/pubmed/37012386
http://dx.doi.org/10.1038/s41514-023-00106-4

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