NAD(+) repletion with niacin counteracts cancer cachexia

Cachexia is a debilitating wasting syndrome and highly prevalent comorbidity in cancer patients. It manifests especially with energy and mitochondrial metabolism aberrations that promote tissue wasting. We recently identified nicotinamide adenine dinucleotide (NAD(+)) loss to associate with muscle m...

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Detalles Bibliográficos
Autores principales: Beltrà, Marc, Pöllänen, Noora, Fornelli, Claudia, Tonttila, Kialiina, Hsu, Myriam Y., Zampieri, Sandra, Moletta, Lucia, Corrà, Samantha, Porporato, Paolo E., Kivelä, Riikka, Viscomi, Carlo, Sandri, Marco, Hulmi, Juha J., Sartori, Roberta, Pirinen, Eija, Penna, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070388/
https://www.ncbi.nlm.nih.gov/pubmed/37012289
http://dx.doi.org/10.1038/s41467-023-37595-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070388/
https://www.ncbi.nlm.nih.gov/pubmed/37012289
http://dx.doi.org/10.1038/s41467-023-37595-6

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