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NAD(+) repletion with niacin counteracts cancer cachexia
Cachexia is a debilitating wasting syndrome and highly prevalent comorbidity in cancer patients. It manifests especially with energy and mitochondrial metabolism aberrations that promote tissue wasting. We recently identified nicotinamide adenine dinucleotide (NAD(+)) loss to associate with muscle m...
Autores principales: | Beltrà, Marc, Pöllänen, Noora, Fornelli, Claudia, Tonttila, Kialiina, Hsu, Myriam Y., Zampieri, Sandra, Moletta, Lucia, Corrà, Samantha, Porporato, Paolo E., Kivelä, Riikka, Viscomi, Carlo, Sandri, Marco, Hulmi, Juha J., Sartori, Roberta, Pirinen, Eija, Penna, Fabio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070388/ https://www.ncbi.nlm.nih.gov/pubmed/37012289 http://dx.doi.org/10.1038/s41467-023-37595-6 |
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