Rewiring of the 3D genome during acquisition of carboplatin resistance in a triple-negative breast cancer patient-derived xenograft

Changes in the three-dimensional (3D) structure of the genome are an emerging hallmark of cancer. Cancer-associated copy number variants and single nucleotide polymorphisms promote rewiring of chromatin loops, disruption of topologically associating domains (TADs), active/inactive chromatin state sw...

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Detalles Bibliográficos
Autores principales: Dozmorov, Mikhail G., Marshall, Maggie A., Rashid, Narmeen S., Grible, Jacqueline M., Valentine, Aaron, Olex, Amy L., Murthy, Kavita, Chakraborty, Abhijit, Reyna, Joaquin, Figueroa, Daniela Salgado, Hinojosa-Gonzalez, Laura, Da-Inn Lee, Erika, Baur, Brittany A., Roy, Sushmita, Ay, Ferhat, Harrell, J. Chuck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070455/
https://www.ncbi.nlm.nih.gov/pubmed/37012431
http://dx.doi.org/10.1038/s41598-023-32568-7

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