Cargando…

In silico study of HASDI (high-affinity selective DNA intercalator) as a new agent capable of highly selective recognition of the DNA sequence

Cancer as an acquired genetic disease is based on changes both in the genome itself and in transcription processes. Accordingly, it is at the DNA level that it makes sense to search for and design agents capable of effective and selective anticancer action. In this study, we used an iterative approa...

Descripción completa

Detalles Bibliográficos
Autores principales: Zaremba, Andrii A., Zaremba, Polina Yu., Zahorodnia, Svitlana D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070485/
https://www.ncbi.nlm.nih.gov/pubmed/37012345
http://dx.doi.org/10.1038/s41598-023-32595-4