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Cell differentiation modifies the p53 transcriptional program through a combination of gene silencing and constitutive transactivation
The p53 transcription factor is a master regulator of cellular responses to stress that is commonly inactivated in diverse cancer types. Despite decades of research, the mechanisms by which p53 impedes tumorigenesis across vastly different cellular contexts requires further investigation. The bulk o...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070495/ https://www.ncbi.nlm.nih.gov/pubmed/36681780 http://dx.doi.org/10.1038/s41418-023-01113-4 |