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Long-term depression in neurons involves temporal and ultra-structural dynamics of phosphatidylinositol-4,5-bisphosphate relying on PIP5K, PTEN and PLC

Synaptic plasticity involves proper establishment and rearrangement of structural and functional microdomains. Yet, visualization of the underlying lipid cues proved challenging. Applying a combination of rapid cryofixation, membrane freeze-fracturing, immunogold labeling and electron microscopy, we...

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Detalles Bibliográficos
Autores principales:	Hofbrucker-MacKenzie, Sarah A., Seemann, Eric, Westermann, Martin, Qualmann, Britta, Kessels, Michael M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070498/ https://www.ncbi.nlm.nih.gov/pubmed/37012315 http://dx.doi.org/10.1038/s42003-023-04726-0

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