Convalescent human IgG, but not IgM, from COVID-19 survivors confers dose-dependent protection against SARS-CoV-2 replication and disease in hamsters

INTRODUCTION: Antibody therapeutic strategies have served an important role during the COVID-19 pandemic, even as their effectiveness has waned with the emergence of escape variants. Here we sought to determine the concentration of convalescent immunoglobulin required to protect against disease from...

Descripción completa

Detalles Bibliográficos
Autores principales: King, Hannah A. D., Dussupt, Vincent, Mendez-Rivera, Letzibeth, Slike, Bonnie M., Tran, Ursula, Jackson, Nathan D., Barkei, Erica, Zemil, Michelle, Tourtellott-Fogt, Emily, Kuklis, Caitlin H., Soman, Sandrine, Ahmed, Aslaa, Porto, Maciel, Kitajewski, Christopher, Spence, Brittany, Benetiene, Dalia, Wieczorek, Lindsay, Kar, Swagata, Gromowski, Gregory, Polonis, Victoria R., Krebs, Shelly J., Modjarrad, Kayvon, Bolton, Diane L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070741/
https://www.ncbi.nlm.nih.gov/pubmed/37026013
http://dx.doi.org/10.3389/fimmu.2023.1138629

Ejemplares similares

Ejemplares similares