Cargando…
UPF3A is dispensable for nonsense-mediated mRNA decay in mouse pluripotent and somatic cells
Nonsense-mediated mRNA decay (NMD) is a highly conserved regulatory mechanism of post-transcriptional gene expression in eukaryotic cells. NMD plays essential roles in mRNA quality and quantity control and thus safeguards multiple biological processes including embryonic stem cell differentiation an...
Autores principales: | Chen, Chengyan, Shen, Yanmin, Li, Luqian, Ren, Yaoxin, Wang, Zhao-Qi, Li, Tangliang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070813/ https://www.ncbi.nlm.nih.gov/pubmed/36997282 http://dx.doi.org/10.26508/lsa.202201589 |
Ejemplares similares
-
UPFront and center in RNA decay: UPF1 in nonsense-mediated mRNA decay and beyond
por: Kim, Yoon Ki, et al.
Publicado: (2019) -
Nonsense-mediated mRNA decay factor UPF1 promotes aggresome formation
por: Park, Yeonkyoung, et al.
Publicado: (2020) -
Human UPF3A and UPF3B enable fault‐tolerant activation of nonsense‐mediated mRNA decay
por: Wallmeroth, Damaris, et al.
Publicado: (2022) -
Hyperphosphorylation amplifies UPF1 activity to resolve stalls in nonsense-mediated mRNA decay
por: Durand, Sébastien, et al.
Publicado: (2016) -
Nonsense-mediated mRNA decay factor Upf2 exists in both the nucleoplasm and the cytoplasm
por: Tatsuno, Takanori, et al.
Publicado: (2017)