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Deep learning-based image segmentation model using an MRI-based convolutional neural network for physiological evaluation of the heart

Background and Objective: Cardiovascular disease is a high-fatality health issue. Accurate measurement of cardiovascular function depends on precise segmentation of physiological structure and accurate evaluation of functional parameters. Structural segmentation of heart images and calculation of th...

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Autores principales: Xu, Wanni, Shi, Jianshe, Lin, Yunling, Liu, Chao, Xie, Weifang, Liu, Huifang, Huang, Siyu, Zhu, Daxin, Su, Lianta, Huang, Yifeng, Ye, Yuguang, Huang, Jianlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070825/
https://www.ncbi.nlm.nih.gov/pubmed/37025385
http://dx.doi.org/10.3389/fphys.2023.1148717
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author Xu, Wanni
Shi, Jianshe
Lin, Yunling
Liu, Chao
Xie, Weifang
Liu, Huifang
Huang, Siyu
Zhu, Daxin
Su, Lianta
Huang, Yifeng
Ye, Yuguang
Huang, Jianlong
author_facet Xu, Wanni
Shi, Jianshe
Lin, Yunling
Liu, Chao
Xie, Weifang
Liu, Huifang
Huang, Siyu
Zhu, Daxin
Su, Lianta
Huang, Yifeng
Ye, Yuguang
Huang, Jianlong
author_sort Xu, Wanni
collection PubMed
description Background and Objective: Cardiovascular disease is a high-fatality health issue. Accurate measurement of cardiovascular function depends on precise segmentation of physiological structure and accurate evaluation of functional parameters. Structural segmentation of heart images and calculation of the volume of different ventricular activity cycles form the basis for quantitative analysis of physiological function and can provide the necessary support for clinical physiological diagnosis, as well as the analysis of various cardiac diseases. Therefore, it is important to develop an efficient heart segmentation algorithm. Methods: A total of 275 nuclear magnetic resonance imaging (MRI) heart scans were collected, analyzed, and preprocessed from Huaqiao University Affiliated Strait Hospital, and the data were used in our improved deep learning model, which was designed based on the U-net network. The training set included 80% of the images, and the remaining 20% was the test set. Based on five time phases from end-diastole (ED) to end-systole (ES), the segmentation findings showed that it is possible to achieve improved segmentation accuracy and computational complexity by segmenting the left ventricle (LV), right ventricle (RV), and myocardium (myo). Results: We improved the Dice index of the LV to 0.965 and 0.921, and the Hausdorff index decreased to 5.4 and 6.9 in the ED and ES phases, respectively; RV Dice increased to 0.938 and 0.860, and the Hausdorff index decreased to 11.7 and 12.6 in the ED and ES, respectively; myo Dice increased to 0.889 and 0.901, and the Hausdorff index decreased to 8.3 and 9.2 in the ED and ES, respectively. Conclusion: The model obtained in the final experiment provided more accurate segmentation of the left and right ventricles, as well as the myocardium, from cardiac MRI. The data from this model facilitate the prediction of cardiovascular disease in real-time, thereby providing potential clinical utility.
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spelling pubmed-100708252023-04-05 Deep learning-based image segmentation model using an MRI-based convolutional neural network for physiological evaluation of the heart Xu, Wanni Shi, Jianshe Lin, Yunling Liu, Chao Xie, Weifang Liu, Huifang Huang, Siyu Zhu, Daxin Su, Lianta Huang, Yifeng Ye, Yuguang Huang, Jianlong Front Physiol Physiology Background and Objective: Cardiovascular disease is a high-fatality health issue. Accurate measurement of cardiovascular function depends on precise segmentation of physiological structure and accurate evaluation of functional parameters. Structural segmentation of heart images and calculation of the volume of different ventricular activity cycles form the basis for quantitative analysis of physiological function and can provide the necessary support for clinical physiological diagnosis, as well as the analysis of various cardiac diseases. Therefore, it is important to develop an efficient heart segmentation algorithm. Methods: A total of 275 nuclear magnetic resonance imaging (MRI) heart scans were collected, analyzed, and preprocessed from Huaqiao University Affiliated Strait Hospital, and the data were used in our improved deep learning model, which was designed based on the U-net network. The training set included 80% of the images, and the remaining 20% was the test set. Based on five time phases from end-diastole (ED) to end-systole (ES), the segmentation findings showed that it is possible to achieve improved segmentation accuracy and computational complexity by segmenting the left ventricle (LV), right ventricle (RV), and myocardium (myo). Results: We improved the Dice index of the LV to 0.965 and 0.921, and the Hausdorff index decreased to 5.4 and 6.9 in the ED and ES phases, respectively; RV Dice increased to 0.938 and 0.860, and the Hausdorff index decreased to 11.7 and 12.6 in the ED and ES, respectively; myo Dice increased to 0.889 and 0.901, and the Hausdorff index decreased to 8.3 and 9.2 in the ED and ES, respectively. Conclusion: The model obtained in the final experiment provided more accurate segmentation of the left and right ventricles, as well as the myocardium, from cardiac MRI. The data from this model facilitate the prediction of cardiovascular disease in real-time, thereby providing potential clinical utility. Frontiers Media S.A. 2023-03-21 /pmc/articles/PMC10070825/ /pubmed/37025385 http://dx.doi.org/10.3389/fphys.2023.1148717 Text en Copyright © 2023 Xu, Shi, Lin, Liu, Xie, Liu, Huang, Zhu, Su, Huang, Ye and Huang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Physiology
Xu, Wanni
Shi, Jianshe
Lin, Yunling
Liu, Chao
Xie, Weifang
Liu, Huifang
Huang, Siyu
Zhu, Daxin
Su, Lianta
Huang, Yifeng
Ye, Yuguang
Huang, Jianlong
Deep learning-based image segmentation model using an MRI-based convolutional neural network for physiological evaluation of the heart
title Deep learning-based image segmentation model using an MRI-based convolutional neural network for physiological evaluation of the heart
title_full Deep learning-based image segmentation model using an MRI-based convolutional neural network for physiological evaluation of the heart
title_fullStr Deep learning-based image segmentation model using an MRI-based convolutional neural network for physiological evaluation of the heart
title_full_unstemmed Deep learning-based image segmentation model using an MRI-based convolutional neural network for physiological evaluation of the heart
title_short Deep learning-based image segmentation model using an MRI-based convolutional neural network for physiological evaluation of the heart
title_sort deep learning-based image segmentation model using an mri-based convolutional neural network for physiological evaluation of the heart
topic Physiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070825/
https://www.ncbi.nlm.nih.gov/pubmed/37025385
http://dx.doi.org/10.3389/fphys.2023.1148717
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