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Matching for HLA-DR excluding diabetogenic HLA-DR3 and HLA-DR4 predicts insulin independence after pancreatic islet transplantation

INTRODUCTION: In pancreatic islet transplantation, the exact contribution of human leukocyte antigen (HLA) matching to graft survival remains unclear. Islets may be exposed to allogenic rejection but also the recurrence of type 1 diabetes (T1D). We evaluated the HLA-DR matching, including the impact...

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Detalles Bibliográficos
Autores principales: Ballou, Cassandra, Barton, Franca, Payne, Elizabeth H., Berney, Thierry, Villard, Jean, Meier, Raphael P. H., Baidal, David, Alejandro, Rodolfo, Robien, Mark, Eggerman, Thomas L., Kamoun, Malek, Muller, Yannick D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070978/
https://www.ncbi.nlm.nih.gov/pubmed/37026004
http://dx.doi.org/10.3389/fimmu.2023.1110544