Distribution of a novel CYP2C haplotype in Native American populations

The CYP2C19 gene, located in the CYP2C cluster, encodes the major drug metabolism enzyme CYP2C19. This gene is highly polymorphic and no-function (CYP2C19*2 and CYP2C19*3), reduced function (CYP2C19*9) and increased function (CYP2C19*17) star alleles (haplotypes) are commonly used to predict CYP2C19...

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Detalles Bibliográficos
Autores principales: Fernandes, Vanessa Câmara, Pretti, Marco Antônio M., Tsuneto, Luiza Tamie, Petzl-Erler, Maria Luiza, Suarez-Kurtz, Guilherme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071019/
https://www.ncbi.nlm.nih.gov/pubmed/37025454
http://dx.doi.org/10.3389/fgene.2023.1114742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071019/
https://www.ncbi.nlm.nih.gov/pubmed/37025454
http://dx.doi.org/10.3389/fgene.2023.1114742

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