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Reduced platelet glycoprotein Ibα shedding accelerates thrombopoiesis and COX-1 recovery: implications for aspirin dosing regimen

Cardiovascular (CV) disease prevention with low-dose aspirin can be less effective in patients with a faster recovery of platelet (PLT) cyclooxygenase (COX)-1 activity during the 24-hour dosing interval. We previously showed that incomplete suppression of TXA(2) over 24 hours can be rescued by a twi...

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Detalles Bibliográficos
Autores principales:	Simeone, Paola, Liani, Rossella, Tripaldi, Romina, Ciotti, Sonia, Recchiuti, Antonio, Abbonante, Vittorio, Porro, Benedetta, Del Boccio, Piero, di Castelnuovo, Augusto, Lanuti, Paola, Camera, Marina, Pieragostino, Damiana, Lee-Sundlov, Melissa, Luongo, Myriam, Auciello, Raffaella, Bologna, Giuseppina, Cufaro, Maria Concetta, Tremoli, Elena, Hoffmeister, Karin M., Cipollone, Francesco, Balduini, Alessandra, Santilli, Francesca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Fondazione Ferrata Storti 2022
Materias:	Article - Platelet Biology & its Disorders
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071111/ https://www.ncbi.nlm.nih.gov/pubmed/36546455 http://dx.doi.org/10.3324/haematol.2022.281006

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