Improving the anti-acute myeloid leukemia activity of CD123-specific engager T cells by MyD88 and CD40 co-stimulation

The outcome of patients with acute myeloid leukemia remains poor, and immunotherapy has the potential to improve this. T cells expressing chimeric antigen receptors or bispecific T-cell engagers targeting CD123 are actively being explored in preclinical and/or early phase clinical studies. We have s...

Descripción completa

Detalles Bibliográficos
Autores principales: Vaidya, Abishek, Doherty, Erin, Wu, Xiya, Huang, Sujuan, Hebbar, Nikhil, Thanekar, Unmesha, Bonifant, Challice L., Cheng, Cheng, Gottschalk, Stephen, Velasquez, M. Paulina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Article - Cell Therapy & Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071120/
https://www.ncbi.nlm.nih.gov/pubmed/35899386
http://dx.doi.org/10.3324/haematol.2021.279301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071120/
https://www.ncbi.nlm.nih.gov/pubmed/35899386
http://dx.doi.org/10.3324/haematol.2021.279301

Ejemplares similares