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A transcriptomics approach to expand therapeutic options and optimize clinical trials in oncology
BACKGROUND: The current model of clinical drug development in oncology displays major limitations due to a high attrition rate in patient enrollment in early phase trials and a high failure rate of drugs in phase III studies. OBJECTIVE: Integrating transcriptomics for selection of patients has the p...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071163/ https://www.ncbi.nlm.nih.gov/pubmed/37025260 http://dx.doi.org/10.1177/17588359231156382 |