A transcriptomics approach to expand therapeutic options and optimize clinical trials in oncology

BACKGROUND: The current model of clinical drug development in oncology displays major limitations due to a high attrition rate in patient enrollment in early phase trials and a high failure rate of drugs in phase III studies. OBJECTIVE: Integrating transcriptomics for selection of patients has the p...

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Detalles Bibliográficos
Autores principales: Lazar, Vladimir, Zhang, Baolin, Magidi, Shai, Le Tourneau, Christophe, Raymond, Eric, Ducreux, Michel, Bresson, Catherine, Raynaud, Jacques, Wunder, Fanny, Onn, Amir, Felip, Enriqueta, Tabernero, Josep, Batist, Gerald, Kurzrock, Razelle, Rubin, Eitan, Schilsky, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Using RNA Sequencing and Profiling in Diagnosis and Treatment of Cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071163/
https://www.ncbi.nlm.nih.gov/pubmed/37025260
http://dx.doi.org/10.1177/17588359231156382

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