Cargando…

The transcription regulator ATF4 is a mediator of skeletal muscle aging

Aging slowly erodes skeletal muscle strength and mass, eventually leading to profound functional deficits and muscle atrophy. The molecular mechanisms of skeletal muscle aging are not well understood. To better understand mechanisms of muscle aging, we investigated the potential role of ATF4, a tran...

Descripción completa

Detalles Bibliográficos
Autores principales:	Miller, Matthew J., Marcotte, George R., Basisty, Nathan, Wehrfritz, Cameron, Ryan, Zachary C., Strub, Matthew D., McKeen, Andrew T., Stern, Jennifer I., Nath, Karl A., Rasmussen, Blake B., Judge, Andrew R., Schilling, Birgit, Ebert, Scott M., Adams, Christopher M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071239/ https://www.ncbi.nlm.nih.gov/pubmed/37014538 http://dx.doi.org/10.1007/s11357-023-00772-y

Ejemplares similares

Activating transcription factor 4 (ATF4) promotes skeletal muscle atrophy by forming a heterodimer with the transcriptional regulator C/EBPβ
por: Ebert, Scott M., et al.
Publicado: (2020)

Comprehensive proteomic quantification of bladder stone progression in a cystinuric mouse model using data-independent acquisitions
por: Rose, Jacob, et al.
Publicado: (2022)

Identifying ubiquitinated proteins and aggregates
por: Basisty, Nathan, et al.
Publicado: (2018)

Accumulation of “Old Proteins” and the Critical Need for MS‐based Protein Turnover Measurements in Aging and Longevity
por: Basisty, Nathan, et al.
Publicado: (2019)

Quantification and Identification of Post-Translational Modifications Using Modern Proteomics Approaches
por: Holtz, Anja, et al.
Publicado: (2021)

Protein Turnover in Aging and Longevity
por: Basisty, Nathan, et al.
Publicado: (2018)

Coenzyme A binding sites induce proximal acylation across protein families
por: Carrico, Chris, et al.
Publicado: (2023)

Quantitative Proteomic Analysis of the Senescence‐Associated Secretory Phenotype by Data‐Independent Acquisition
por: Neri, Francesco, et al.
Publicado: (2021)

Simultaneous Quantification of the Acetylome and Succinylome by ‘One‐Pot’ Affinity Enrichment
por: Basisty, Nathan, et al.
Publicado: (2018)

Introduction to Food Irradiation and Medical Sterilization
por: McKeen, Laurence
Publicado: (2012)

SASP PROTEIN ASSOCIATIONS WITH HUMAN AGING HIGHLIGHTS THE ROLE OF GDF15, CST3, AND IGFBP2
por: Evans, Daniel, et al.
Publicado: (2022)

Skeletal Muscle Fibrosis in Pancreatic Cancer Patients with Respect to Survival
por: Judge, Sarah M, et al.
Publicado: (2019)

The effect of temperature and other factors on plastics and elastomers
por: McKeen, Laurence W
Publicado: (2014)

Fatigue and tribological properties of plastics and elastomers
por: McKeen, Laurence W
Publicado: (2010)

Review effect on cost reports: Impact smaller than anticipated
por: Cowles, C. McKeen
Publicado: (1991)

Proteomic Analysis of Huntington’s Disease Medium Spiny Neurons Identifies Alterations in Lipid Droplets
por: Tshilenge, Kizito-Tshitoko, et al.
Publicado: (2023)

Identification and Small Molecule Inhibition of an Activating Transcription Factor 4 (ATF4)-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy
por: Ebert, Scott M., et al.
Publicado: (2015)

Supporting vulnerable physicians at high risk from COVID-19 during the pandemic: a call for action
por: Singh, Mandeep, et al.
Publicado: (2021)

Stable nuclear expression of ATP8 and ATP6 genes rescues a mtDNA Complex V null mutant
por: Boominathan, Amutha, et al.
Publicado: (2016)

Post-translational Protein Acetylation: An Elegant Mechanism for Bacteria to Dynamically Regulate Metabolic Functions
por: Christensen, David G., et al.
Publicado: (2019)

Response to: No community left behind: advancing rural anesthesia, surgery, and obstetric care in Canada
por: McKeen, Dolores M., et al.
Publicado: (2022)

Beam Jitter Studies at ATF and ATF2
por: Pfingstner, Jürgen, et al.
Publicado: (2013)

Temporal dynamics of liver mitochondrial protein acetylation and succinylation and metabolites due to high fat diet and/or excess glucose or fructose
por: Meyer, Jesse G., et al.
Publicado: (2018)

Management challenges in IS: successful strategies and appropriate action
por: McKeen, James D, et al.
Publicado: (1996)

Depleting Ly6G Positive Myeloid Cells Reduces Pancreatic Cancer-Induced Skeletal Muscle Atrophy
por: Deyhle, Michael R., et al.
Publicado: (2022)

Plasma proteomic biomarker signature of age predicts health and life span
por: Tanaka, Toshiko, et al.
Publicado: (2020)

ATF5 is a regulator of exercise-induced mitochondrial quality control in skeletal muscle
por: Slavin, Mikhaela B., et al.
Publicado: (2022)

ATF2 and ATF7 Are Critical Mediators of Intestinal Epithelial Repair
por: Meijer, Bartolomeus J., et al.
Publicado: (2020)

Identification of the Acetylation and Ubiquitin-Modified Proteome during the Progression of Skeletal Muscle Atrophy
por: Ryder, Daniel J., et al.
Publicado: (2015)

Quality gaps in screening and monitoring for postoperative hyperglycemia in a Canadian hospital: a retrospective cohort study
por: Ruzycki, Shannon M, et al.
Publicado: (2021)

Gadd45a Protein Promotes Skeletal Muscle Atrophy by Forming a Complex with the Protein Kinase MEKK4
por: Bullard, Steven A., et al.
Publicado: (2016)

Genetic Interactions Between Aspergillus fumigatus Basic Leucine Zipper (bZIP) Transcription Factors AtfA, AtfB, AtfC, and AtfD
por: Silva, Lilian Pereira, et al.
Publicado: (2021)

ATF2 COMMISSIONING
por: Seryi, A, et al.
Publicado: (2010)

Effect of AAV-mediated overexpression of ATF5 and downstream targets of an integrated stress response in murine skeletal muscle
por: Brearley-Sholto, Madelaine C., et al.
Publicado: (2021)

A Cytoplasmic Negative Regulator Isoform of ATF7 Impairs ATF7 and ATF2 Phosphorylation and Transcriptional Activity
por: Diring, Jessica, et al.
Publicado: (2011)

Proteomics in aging research: A roadmap to clinical, translational research
por: Moaddel, Ruin, et al.
Publicado: (2021)

Status of the ATF2 Lattices
por: Marin, E, et al.
Publicado: (2011)

Intrathecal hyperbaric versus isobaric bupivacaine for adult non-caesarean-section surgery: systematic review protocol
por: Uppal, Vishal, et al.
Publicado: (2016)

Role and Mechanisms of Mitophagy in Liver Diseases
por: Ma, Xiaowen, et al.
Publicado: (2020)

Was it Good for You? Gender Differences in Motives and Emotional Outcomes Following Casual Sex
por: McKeen, Billie E., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_jfdej23jaj8spafqg5q193hug3