Inhibition of angiotensin converting enzyme increases PKCβI isoform expression via activation of substance P and bradykinin receptors in cultured astrocytes of mice

BACKGROUND: Angiotensin-converting enzyme inhibitor (ACEi) inhibits the catalysis of angiotensin I to angiotensin II and the degradation of substance P (SP) and bradykinin (BK). While the possible relationship between ACEi and SP in nociceptive mice was recently suggested, the effect of ACEi on sign...

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Detalles Bibliográficos
Autores principales: Choi, Jae-Gyun, Choi, Sheu-Ran, Kang, Dong-Wook, Shin, Hyun Jin, Lee, Miae, Hwang, Jungmo, Kim, Hyun-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Veterinary Science 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071283/
https://www.ncbi.nlm.nih.gov/pubmed/37012034
http://dx.doi.org/10.4142/jvs.22275

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