Cargando…

Combretastatins D series and analogues: from isolation, synthetic challenges and biological activities

The combretastatin D series and its analogues, corniculatolides and isocorniculatolides belong to a class of macrocycles called cyclic diaryl ether heptanoids (DAEH). This review is intended to highlight the structure elucidation, biosynthesis, and biological activity of these compounds as well as t...

Descripción completa

Detalles Bibliográficos
Autores principales: de Lima Neto, Jorge, Menezes, Paulo Henrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071520/
https://www.ncbi.nlm.nih.gov/pubmed/37025497
http://dx.doi.org/10.3762/bjoc.19.31
Descripción
Sumario:The combretastatin D series and its analogues, corniculatolides and isocorniculatolides belong to a class of macrocycles called cyclic diaryl ether heptanoids (DAEH). This review is intended to highlight the structure elucidation, biosynthesis, and biological activity of these compounds as well as the use of different strategies for their synthesis.