Cargando…

Association of polygenic risk score with response to deep brain stimulation in Parkinson’s disease

BACKGROUND: Deep brain stimulation (DBS) is a well-established treatment option for select patients with Parkinson’s Disease (PD). However, response to DBS varies, therefore, the ability to predict who will have better outcomes can aid patient selection. Some PD-related monogenic mutations have been...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yoon, Esther, Ahmed, Sarah, Li, Ryan, Bandres-Ciga, Sara, Blauwendraat, Cornelis, Dustin, Irene, Scholz, Sonja, Hallett, Mark, Ehrlich, Debra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071605/ https://www.ncbi.nlm.nih.gov/pubmed/37016359 http://dx.doi.org/10.1186/s12883-023-03188-5

Ejemplares similares

Bidirectional relationship between olfaction and Parkinson’s disease
por: Kim, Jonggeol J., et al.
Publicado: (2023)

Polygenic Resilience Modulates the Penetrance of Parkinson Disease Genetic Risk Factors
por: Liu, Hui, et al.
Publicado: (2022)

MIDN locus structural variants and Parkinson's Disease risk
por: Billingsley, Kimberley J., et al.
Publicado: (2020)

Analysis of rare Parkinson’s disease variants in millions of people
por: Pitz, Vanessa, et al.
Publicado: (2023)

Lower Lymphocyte Count is Associated With Increased Risk of Parkinson’s Disease
por: Jensen, Melanie P., et al.
Publicado: (2021)

Insights on Genetic and Environmental Factors in Parkinson’s Disease from a Regional Swedish Case-Control Cohort
por: Brolin, Kajsa, et al.
Publicado: (2022)

Black and African American Connections to Parkinson's Disease Study: Addressing Missing Diversity in Parkinson's Disease Genetics
por: Bandres‐Ciga, Sara
Publicado: (2022)

Effect Modification between Genes and Environment and Parkinson's Disease Risk
por: Periñán, Maria Teresa, et al.
Publicado: (2022)

Unhealthy Behaviours and Risk of Parkinson’s Disease: A Mendelian Randomisation Study
por: Heilbron, Karl, et al.
Publicado: (2021)

Large-scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease
por: Bandres-Ciga, S., et al.
Publicado: (2020)

Correction to: Large‑scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease
por: Bandres-Ciga, S., et al.
Publicado: (2021)

RIC3 variants are not associated with Parkinson’s disease in large European, Latin American, or East Asian cohorts
por: Brolin, Kajsa, et al.
Publicado: (2022)

The Genetic Landscape of Parkinsonism-Related Dystonias and Atypical Parkinsonism-Related Syndromes
por: Diez-Fairen, Monica, et al.
Publicado: (2021)

The Parkinson's Disease DNA Variant Browser
por: Kim, Jonggeol J., et al.
Publicado: (2021)

Immunogenetic Determinants of Parkinson’s Disease Etiology
por: Kung, Pin-Jui, et al.
Publicado: (2022)

Parkinson’s disease determinants, prediction and gene–environment interactions in the UK Biobank
por: Jacobs, Benjamin Meir, et al.
Publicado: (2020)

Identification and prediction of Parkinson’s disease subtypes and progression using machine learning in two cohorts
por: Dadu, Anant, et al.
Publicado: (2022)

Mapping the Diverse and Inclusive Future of Parkinson’s Disease Genetics and Its Widespread Impact
por: Elsayed, Inas, et al.
Publicado: (2021)

Advancing Personalized Medicine in Common Forms of Parkinson’s Disease through Genetics: Current Therapeutics and the Future of Individualized Management
por: Reed, Xylena, et al.
Publicado: (2021)

A population scale analysis of rare SNCA variation in the UK Biobank
por: Blauwendraat, Cornelis, et al.
Publicado: (2020)

Genetic risk factor clustering within and across neurodegenerative diseases
por: Koretsky, Mathew J, et al.
Publicado: (2023)

Evaluating Lipid‐Lowering Drug Targets for Parkinson's Disease Prevention with Mendelian Randomization
por: Williams, Dylan M., et al.
Publicado: (2020)

Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis
por: Bandres‐Ciga, Sara, et al.
Publicado: (2019)

Unraveling the genetic complexity of Alzheimer disease with Mendelian Randomization
por: Bandres-Ciga, Sara, et al.
Publicado: (2019)

Nutritional Ketosis in Parkinson’s Disease — a Review of Remaining Questions and Insights
por: Choi, Alexander, et al.
Publicado: (2021)

Genetic Risk Profiling in Parkinson’s Disease and Utilizing Genetics to Gain Insight into Disease-Related Biological Pathways
por: Hall, Ashley, et al.
Publicado: (2020)

Polygenic Risk Scores Contribute to Personalized Medicine of Parkinson’s Disease
por: Dehestani, Mohammad, et al.
Publicado: (2021)

Mitochondria function associated genes contribute to Parkinson’s Disease risk and later age at onset
por: Billingsley, Kimberley J., et al.
Publicado: (2019)

Tumor Necrosis Factor Inhibition and Parkinson Disease: A Mendelian Randomization Study
por: Kang, Xiaoying, et al.
Publicado: (2021)

Validity and Prognostic Value of a Polygenic Risk Score for Parkinson’s Disease
por: Koch, Sebastian, et al.
Publicado: (2021)

PTPA variants and the risk for Parkinson’s disease in diverse ancestry populations
por: Ostrožovičová, Miriam, et al.
Publicado: (2023)

The Parkinson's Disease Mendelian Randomization Research Portal
por: Noyce, Alastair J., et al.
Publicado: (2019)

Exploring the genetic and genomic connection underlying neurodegeneration with brain iron accumulation and the risk for Parkinson’s disease
por: Alvarez Jerez, Pilar, et al.
Publicado: (2023)

Heritability Enrichment Implicates Microglia in Parkinson’s Disease Pathogenesis
por: Andersen, Maren Stolp, et al.
Publicado: (2021)

Finding genetically-supported drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome
por: Storm, Catherine S., et al.
Publicado: (2021)

Headaches and polygenic scores
por: Vilhjálmsson, Bjarni J., et al.
Publicado: (2019)

Type 2 Diabetes as a Determinant of Parkinson’s Disease Risk and Progression
por: Chohan, Harneek, et al.
Publicado: (2021)

Association of the Polygenic Risk Score With the Probability of Prodromal Parkinson’s Disease in Older Adults
por: Maraki, Maria I., et al.
Publicado: (2021)

The combined effect of lifestyle factors and polygenic scores on age at onset in Parkinson’s disease
por: Gabbert, Carolin, et al.
Publicado: (2023)

Performance of Polygenic Scores for Predicting Phobic Anxiety
por: Walter, Stefan, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_tkj449jm65nothnkj9oqnlqvlc