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Mechanical overloading-induced miR-325-3p reduction promoted chondrocyte senescence and exacerbated facet joint degeneration

OBJECTIVE: Lumbar facet joint (LFJ) degeneration is one of the main causes of low back pain (LBP). Mechanical stress leads to the exacerbation of LFJ degeneration, but the underlying mechanism remains unknown. This study was intended to investigate the mechanism of LFJ degeneration induced by mechan...

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Detalles Bibliográficos
Autores principales:	Zhao, Jinyun, Li, Chengjun, Qin, Tian, Jin, Yuxin, He, Rundong, Sun, Yi, Liu, Zhide, Wu, Tianding, Duan, Chunyue, Cao, Yong, Hu, Jianzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071751/ https://www.ncbi.nlm.nih.gov/pubmed/37016437 http://dx.doi.org/10.1186/s13075-023-03037-3

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