CD73-Dependent Adenosine Signaling through Adora2b Drives Immunosuppression in Ductal Pancreatic Cancer

The microenvironment that surrounds pancreatic ductal adenocarcinoma (PDAC) is profoundly desmoplastic and immunosuppressive. Understanding triggers of immunosuppression during the process of pancreatic tumorigenesis would aid in establishing targets for effective prevention and therapy. Here, we in...

Descripción completa

Detalles Bibliográficos
Autores principales: Faraoni, Erika Y., Singh, Kanchan, Chandra, Vidhi, Le Roux, Olivereen, Dai, Yulin, Sahin, Ismet, O'Brien, Baylee J., Strickland, Lincoln N., Li, Le, Vucic, Emily, Warner, Amanda N., Pruski, Melissa, Clark, Trent, Van Buren, George, Thosani, Nirav C., Bynon, John S., Wray, Curtis J., Bar-Sagi, Dafna, Poulsen, Kyle L., Vornik, Lana A., Savage, Michelle I., Sei, Shizuko, Mohammed, Altaf, Zhao, Zhongming, Brown, Powel H., Mills, Tingting, Eltzschig, Holger K., McAllister, Florencia, Bailey-Lundberg, Jennifer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Tumor Biology and Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071819/
https://www.ncbi.nlm.nih.gov/pubmed/36720042
http://dx.doi.org/10.1158/0008-5472.CAN-22-2553

Ejemplares similares

Ejemplares similares