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One-pot biosynthesis of N-acetylneuraminic acid from chitin via combination of chitin-degrading enzymes, N-acetylglucosamine-2-epimerase, and N-neuraminic acid aldolase

N-acetylneuraminic acid (Neu5Ac) possesses the ability to promote mental health and enhance immunity and is widely used in both medicine and food fields as a supplement. Enzymatic production of Neu5Ac using N-acetyl-D-glucosamine (GlcNAc) as substrate was significant. However, the high-cost GlcNAc l...

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Detalles Bibliográficos
Autores principales: Liu, Quanzhen, Wei, Guoguang, Yang, Pengfan, Wang, Chengyong, Chen, Kequan, Ouyang, Pingkai, Zhang, Alei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072123/
https://www.ncbi.nlm.nih.gov/pubmed/37025634
http://dx.doi.org/10.3389/fmicb.2023.1156924