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Sensing its own permeant ion: KCNQ1 channel inhibition by external K(+)

External potassium inhibits KCNQ1 channel through a mechanism involving increased occupancy of the filter S0 site by K(+)(o).

Detalles Bibliográficos
Autor principal: Barro-Soria, Rene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072219/
https://www.ncbi.nlm.nih.gov/pubmed/36961346
http://dx.doi.org/10.1085/jgp.202313337
Descripción
Sumario:External potassium inhibits KCNQ1 channel through a mechanism involving increased occupancy of the filter S0 site by K(+)(o).