Inclusion of minor alleles improves catalogue-based prediction of fluoroquinolone resistance in Mycobacterium tuberculosis

OBJECTIVES: Fluoroquinolone resistance poses a threat to the successful treatment of tuberculosis. WGS, and the subsequent detection of catalogued resistance-associated mutations, offers an attractive solution to fluoroquinolone susceptibility testing but sensitivities are often less than 90%. We hy...

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Detalles Bibliográficos
Autores principales: Brankin, Alice E, Fowler, Philip W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072237/
https://www.ncbi.nlm.nih.gov/pubmed/37025302
http://dx.doi.org/10.1093/jacamr/dlad039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072237/
https://www.ncbi.nlm.nih.gov/pubmed/37025302
http://dx.doi.org/10.1093/jacamr/dlad039

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