The peculiar challenge of bringing CAR-T cells into the brain: Perspectives in the clinical application to the treatment of pediatric central nervous system tumors

Childhood malignant brain tumors remain a significant cause of death in the pediatric population, despite the use of aggressive multimodal treatments. New therapeutic approaches are urgently needed for these patients in order to improve prognosis, while reducing side effects and long-term sequelae o...

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Detalles Bibliográficos
Autores principales: Del Baldo, Giada, Del Bufalo, Francesca, Pinacchio, Claudia, Carai, Andrea, Quintarelli, Concetta, De Angelis, Biagio, Merli, Pietro, Cacchione, Antonella, Locatelli, Franco, Mastronuzzi, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072260/
https://www.ncbi.nlm.nih.gov/pubmed/37025994
http://dx.doi.org/10.3389/fimmu.2023.1142597

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