Prolonged exposure of neonatal mice to sevoflurane leads to hyper-ramification in microglia, reduced contacts between microglia and synapses, and defects in adult behavior

BACKGROUND: Prolonged exposure to general anesthetics during development is known to cause neurobehavioral abnormalities, but the cellular and molecular mechanisms involved are unclear. Microglia are the resident immune cells in the central nervous system and play essential roles in normal brain dev...

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Detalles Bibliográficos
Autores principales: Li, Hong, Zhou, Bin, Liao, Ping, Liao, Daqing, Yang, Linghui, Wang, Jing, Liu, Jin, Jiang, Ruotian, Chen, Lingmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072331/
https://www.ncbi.nlm.nih.gov/pubmed/37025197
http://dx.doi.org/10.3389/fneur.2023.1142739

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