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Conditional permeabilization of the P. falciparum plasma membrane in infected cells links cation influx to reduced membrane integrity
The intracellular human malaria parasite, Plasmodium falciparum, uses the PfATP4 cation pump to maintain Na(+) and H(+) homeostasis in parasite cytosol. PfATP4 is the target of advanced antimalarial leads, which produce many poorly understood metabolic disturbances within infected erythrocytes. Here...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072447/ https://www.ncbi.nlm.nih.gov/pubmed/37014920 http://dx.doi.org/10.1371/journal.pone.0283776 |