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Primary Squamous Cell Carcinoma of Gallbladder With Hepatic Invasion
Squamous cell carcinoma of the gallbladder is a profoundly rare tumor. It is one of the most aggressive and deadly forms of gallbladder cancer, often being diagnosed at a later stage. There are no definitive risk factors described for this specific type of gallbladder tumor when compared to other fo...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072881/ https://www.ncbi.nlm.nih.gov/pubmed/37025738 http://dx.doi.org/10.7759/cureus.35795 |
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author | Willson, Conner M Barsoum, Nathalie Khan, Mustafa Tamim Alam Rushton, Jennifer |
author_facet | Willson, Conner M Barsoum, Nathalie Khan, Mustafa Tamim Alam Rushton, Jennifer |
author_sort | Willson, Conner M |
collection | PubMed |
description | Squamous cell carcinoma of the gallbladder is a profoundly rare tumor. It is one of the most aggressive and deadly forms of gallbladder cancer, often being diagnosed at a later stage. There are no definitive risk factors described for this specific type of gallbladder tumor when compared to other forms of gallbladder carcinoma. This case is regarding a 64-year-old female who was found to have primary squamous cell carcinoma of the gallbladder during an attempted cholecystectomy. Her tumor was found to have invaded her liver. The tumor displayed characteristic qualities of a pure squamous cell carcinoma and was positive for CK7 and p63 upon pathological analysis. Best results for treatment for this condition are achieved via R0 resection. Adjuvant therapy with chemoradiation has not been well-defined nor very effective in prior cases. |
format | Online Article Text |
id | pubmed-10072881 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-100728812023-04-05 Primary Squamous Cell Carcinoma of Gallbladder With Hepatic Invasion Willson, Conner M Barsoum, Nathalie Khan, Mustafa Tamim Alam Rushton, Jennifer Cureus Pathology Squamous cell carcinoma of the gallbladder is a profoundly rare tumor. It is one of the most aggressive and deadly forms of gallbladder cancer, often being diagnosed at a later stage. There are no definitive risk factors described for this specific type of gallbladder tumor when compared to other forms of gallbladder carcinoma. This case is regarding a 64-year-old female who was found to have primary squamous cell carcinoma of the gallbladder during an attempted cholecystectomy. Her tumor was found to have invaded her liver. The tumor displayed characteristic qualities of a pure squamous cell carcinoma and was positive for CK7 and p63 upon pathological analysis. Best results for treatment for this condition are achieved via R0 resection. Adjuvant therapy with chemoradiation has not been well-defined nor very effective in prior cases. Cureus 2023-03-05 /pmc/articles/PMC10072881/ /pubmed/37025738 http://dx.doi.org/10.7759/cureus.35795 Text en Copyright © 2023, Willson et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Pathology Willson, Conner M Barsoum, Nathalie Khan, Mustafa Tamim Alam Rushton, Jennifer Primary Squamous Cell Carcinoma of Gallbladder With Hepatic Invasion |
title | Primary Squamous Cell Carcinoma of Gallbladder With Hepatic Invasion |
title_full | Primary Squamous Cell Carcinoma of Gallbladder With Hepatic Invasion |
title_fullStr | Primary Squamous Cell Carcinoma of Gallbladder With Hepatic Invasion |
title_full_unstemmed | Primary Squamous Cell Carcinoma of Gallbladder With Hepatic Invasion |
title_short | Primary Squamous Cell Carcinoma of Gallbladder With Hepatic Invasion |
title_sort | primary squamous cell carcinoma of gallbladder with hepatic invasion |
topic | Pathology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072881/ https://www.ncbi.nlm.nih.gov/pubmed/37025738 http://dx.doi.org/10.7759/cureus.35795 |
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