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Known sequence features explain half of all human gene ends

Cleavage and polyadenylation (CPA) sites define eukaryotic gene ends. CPA sites are associated with five key sequence recognition elements: the upstream UGUA, the polyadenylation signal (PAS), and U-rich sequences; the CA/UA dinucleotide where cleavage occurs; and GU-rich downstream elements (DSEs)....

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Detalles Bibliográficos
Autores principales: Shkurin, Aleksei, Pour, Sara E, Hughes, Timothy R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072996/
https://www.ncbi.nlm.nih.gov/pubmed/37035540
http://dx.doi.org/10.1093/nargab/lqad031