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Knockout mice are an important tool for human monogenic heart disease studies

Mouse models are relevant to studying the functionality of genes involved in human diseases; however, translation of phenotypes can be challenging. Here, we investigated genes related to monogenic forms of cardiovascular disease based on the Genomics England PanelApp and aligned them to Internationa...

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Detalles Bibliográficos
Autores principales: Cacheiro, Pilar, Spielmann, Nadine, Mashhadi, Hamed Haseli, Fuchs, Helmut, Gailus-Durner, Valerie, Smedley, Damian, de Angelis, Martin Hrabĕ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073007/
https://www.ncbi.nlm.nih.gov/pubmed/36825469
http://dx.doi.org/10.1242/dmm.049770

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