Cross-reactivity of glycan-reactive HIV-1 broadly neutralizing antibodies with parasite glycans

The HIV-1 Envelope glycoprotein (Env) is the sole target for broadly neutralizing antibodies (bnAbs). Env is heavily glycosylated with host-derived N-glycans, and many bnAbs bind to, or are dependent upon, Env glycans for neutralization. Although glycan-binding bnAbs are frequently detected in HIV-i...

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Detalles Bibliográficos
Autores principales: Huettner, Isabella, Krumm, Stefanie A., Serna, Sonia, Brzezicka, Katarzyna, Monaco, Serena, Walpole, Samuel, van Diepen, Angela, Allan, Fiona, Hicks, Thomas, Kimuda, Simon, Emery, Aidan M., Landais, Elise, Hokke, Cornelis H., Angulo, Jesus, Reichardt, Niels, Doores, Katie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073069/
https://www.ncbi.nlm.nih.gov/pubmed/35354052
http://dx.doi.org/10.1016/j.celrep.2022.110611

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