Cargando…

Recent insights into the crosstalk between senescent cells and CD8 T lymphocytes

Recent reports in oncological and non-oncological experimental setups provide strong evidence that senescent cells are under the surveillance of CD8 T cell-mediated adaptive immunity. These new data also shed light on the mechanisms that sensitize senescent cells to CD8 T cell-dependent killing, as...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marin, Ines, Serrano, Manuel, Pietrocola, Federico
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Comment
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073090/ https://www.ncbi.nlm.nih.gov/pubmed/37015935 http://dx.doi.org/10.1038/s41514-023-00105-5

Ejemplares similares

Cellular senescence enhances adaptive anticancer immunosurveillance
por: Marin, Ines, et al.
Publicado: (2022)

T follicular helper and B cell crosstalk in tertiary lymphoid structures and cancer immunotherapy
por: Garaud, Soizic, et al.
Publicado: (2022)

Is aberrant CD8+ T cell activation by hypertension associated with cardiac injury in severe cases of COVID-19?
por: Zhang, Chao, et al.
Publicado: (2020)

Hypothesis: the subcellular senescence sequence of a mesophyll cell mirrors the cell origin and evolution
por: Gan, Su-Sheng
Publicado: (2022)

Unbiased transcriptomes of resting human CD4(+)CD45RO(+) T lymphocytes
por: Westendorf, Kerstin, et al.
Publicado: (2014)

The grace of aging with ART: Ex vivo dendritic cell-based immunotherapy restores HIV-specific functional CD8(+) T-cells
por: Mehraj, Vikram, et al.
Publicado: (2022)

Sustained CD28 Expression Delays Multiple Features of Replicative Senescence in Human CD8 T Lymphocytes
por: Parish, Stanley T., et al.
Publicado: (2010)

Cellular Senescence Is Immunogenic and Promotes Antitumor Immunity
por: Marin, Ines, et al.
Publicado: (2023)

CD56(dim)CD16(dim) Natural Killer (NK) Cells: The Forgotten Population
por: Zimmer, Jacques
Publicado: (2020)

TP53 Mutations and Clinical Outcome in Chronic Lymphocytic Leukemia: Is a Threshold Still Needed?
por: Bomben, Riccardo, et al.
Publicado: (2023)

The relationship between insomnia and complex diseases—insights from genetic data
por: Byrne, Enda M.
Publicado: (2019)

Bidirectional lysosome transport: a balancing act between ARL8 effectors
por: Kendrick, Agnieszka A., et al.
Publicado: (2022)

New insights into the association between body-mass index and severe COVID-19
por: Bhaskaran, Krishnan
Publicado: (2021)

Cellular senescence and the host immune system in aging and age-related disorders
por: Giannoula, Yvonne, et al.
Publicado: (2023)

Mitochondrial dysfunction and cell senescence — skin deep into mammalian aging
por: Passos, Joao F., et al.
Publicado: (2012)

Changes in neutrophil-lymphocyte and platelet-lymphocyte ratios before and after percutaneous coronary intervention and their impact on the prognosis of patients with acute coronary syndrome
por: Souza Teixeira, Edenilson de, et al.
Publicado: (2023)

Recent advances in uncovering the mechanisms contributing to BIRD-2-induced cell death in B-cell cancer cells
por: Kerkhofs, Martijn, et al.
Publicado: (2019)

Healthy aging—would cytotoxic T lymphocytes stand out?
por: Zhang, Tianyu, et al.
Publicado: (2023)

The lysosomal proteome of senescent cells contributes to the senescence secretome
por: Rovira, Miguel, et al.
Publicado: (2022)

Novel insights into the HLA class I immunopeptidome and T-cell immunosurveillance
por: Melief, Cornelis J. M., et al.
Publicado: (2017)

Following hearts, one cell at a time: recent applications of single-cell RNA sequencing to the understanding of heart disease
por: Ackers-Johnson, Matthew, et al.
Publicado: (2018)

High-throughput sequencing insights into T-cell receptor repertoire diversity in aging
por: Goronzy, Jörg J., et al.
Publicado: (2015)

Recent clinical trials inform the future for malaria vaccines
por: Kurtovic, Liriye, et al.
Publicado: (2021)

Comments on: “What Is Developmental Dyslexia?” Brain Sci. 2018, 8, 26. The Relationship between Eye Movements and Reading Difficulties
por: Blythe, Hazel I., et al.
Publicado: (2018)

Natural selection at the cellular level: insights from male germ cell differentiation
por: Nguyen, Daniel H., et al.
Publicado: (2021)

Putting the Heat on Cardiac Fibrosis: Hsp20 Regulates Myocyte-To-Fibroblast Crosstalk
por: Major, Jennifer L., et al.
Publicado: (2019)

Special features of quantification of CD8(+)CD38(+) T-cells by flow cytometry does not represent a good biomarker to monitor the reactivation of cytomegalovirus infection after allogeneic hematopoietic stem cell transplantation
por: Martins Filho, Olindo Assis
Publicado: (2011)

Seismic insights into Earth’s core
por: Waszek, Lauren, et al.
Publicado: (2023)

CD8(+) T‐cell senescence and skewed lymphocyte subsets in young Dyskeratosis Congenita patients with PARN and DKC1 mutations
por: Zeng, Ting, et al.
Publicado: (2020)

Crosstalk between tumor cells and lymphocytes modulates heparanase expression
por: Theodoro, Thérèse Rachell, et al.
Publicado: (2019)

Autopsy insights from the EVALI epidemic
por: Blagev, Denitza P, et al.
Publicado: (2020)

Recent trends in Pediatric Hematology Oncology fellowship match and the workforce impact
por: Moerdler, Scott, et al.
Publicado: (2021)

Artificial intelligence biomarkers for digital oncology: a case study of tumor-infiltrating lymphocytes in melanoma
por: Salgado, Roberto, et al.
Publicado: (2023)

Spermidine rejuvenates T lymphocytes and restores anticancer immunosurveillance in aged mice
por: Castoldi, Francesca, et al.
Publicado: (2022)

Temozolomide in Glioblastoma Therapy: Role of Apoptosis, Senescence and Autophagy. Comment on Strobel et al., Temozolomide and Other Alkylating Agents in Glioblastoma Therapy. Biomedicines 2019, 7, 69
por: Kaina, Bernd
Publicado: (2019)

CD24Fc: an emerging COVID-19 therapy
por: Eckhardt, Christina M, et al.
Publicado: (2022)

Insights and achievements from the Tara Pacific expedition
por: Planes, Serge, et al.
Publicado: (2023)

Senescence‐associated β‐galactosidase reveals the abundance of senescent CD8+ T cells in aging humans
por: Martínez‐Zamudio, Ricardo I., et al.
Publicado: (2021)

Fisetin as a Senotherapeutic Agent: Biopharmaceutical Properties and Crosstalk between Cell Senescence and Neuroprotection
por: Elsallabi, Osama, et al.
Publicado: (2022)

Allotransplantation Is Associated With Exacerbation of CD8 T-Cell Senescence: The Particular Place of the Innate CD8 T-Cell Component
por: Daniel, Lauren, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_54p6pk8guugm7osq6vahh8hab1