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Exploiting volumetric wave correlation for enhanced depth imaging in scattering medium

Imaging an object embedded within a scattering medium requires the correction of complex sample-induced wave distortions. Existing approaches have been designed to resolve them by optimizing signal waves recorded in each 2D image. Here, we present a volumetric image reconstruction framework that mer...

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Autores principales: Lee, Ye-Ryoung, Kim, Dong-Young, Jo, Yonghyeon, Kim, Moonseok, Choi, Wonshik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073116/
https://www.ncbi.nlm.nih.gov/pubmed/37015941
http://dx.doi.org/10.1038/s41467-023-37467-z
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author Lee, Ye-Ryoung
Kim, Dong-Young
Jo, Yonghyeon
Kim, Moonseok
Choi, Wonshik
author_facet Lee, Ye-Ryoung
Kim, Dong-Young
Jo, Yonghyeon
Kim, Moonseok
Choi, Wonshik
author_sort Lee, Ye-Ryoung
collection PubMed
description Imaging an object embedded within a scattering medium requires the correction of complex sample-induced wave distortions. Existing approaches have been designed to resolve them by optimizing signal waves recorded in each 2D image. Here, we present a volumetric image reconstruction framework that merges two fundamental degrees of freedom, the wavelength and propagation angles of light waves, based on the object momentum conservation principle. On this basis, we propose methods for exploiting the correlation of signal waves from volumetric images to better cope with multiple scattering. By constructing experimental systems scanning both wavelength and illumination angle of the light source, we demonstrated a 32-fold increase in the use of signal waves compared with that of existing 2D-based approaches and achieved ultrahigh volumetric resolution (lateral resolution: 0.41 [Formula: see text] , axial resolution: 0.60 [Formula: see text] ) even within complex scattering medium owing to the optimal coherent use of the broad spectral bandwidth (225 nm).
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spelling pubmed-100731162023-04-06 Exploiting volumetric wave correlation for enhanced depth imaging in scattering medium Lee, Ye-Ryoung Kim, Dong-Young Jo, Yonghyeon Kim, Moonseok Choi, Wonshik Nat Commun Article Imaging an object embedded within a scattering medium requires the correction of complex sample-induced wave distortions. Existing approaches have been designed to resolve them by optimizing signal waves recorded in each 2D image. Here, we present a volumetric image reconstruction framework that merges two fundamental degrees of freedom, the wavelength and propagation angles of light waves, based on the object momentum conservation principle. On this basis, we propose methods for exploiting the correlation of signal waves from volumetric images to better cope with multiple scattering. By constructing experimental systems scanning both wavelength and illumination angle of the light source, we demonstrated a 32-fold increase in the use of signal waves compared with that of existing 2D-based approaches and achieved ultrahigh volumetric resolution (lateral resolution: 0.41 [Formula: see text] , axial resolution: 0.60 [Formula: see text] ) even within complex scattering medium owing to the optimal coherent use of the broad spectral bandwidth (225 nm). Nature Publishing Group UK 2023-04-04 /pmc/articles/PMC10073116/ /pubmed/37015941 http://dx.doi.org/10.1038/s41467-023-37467-z Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Lee, Ye-Ryoung
Kim, Dong-Young
Jo, Yonghyeon
Kim, Moonseok
Choi, Wonshik
Exploiting volumetric wave correlation for enhanced depth imaging in scattering medium
title Exploiting volumetric wave correlation for enhanced depth imaging in scattering medium
title_full Exploiting volumetric wave correlation for enhanced depth imaging in scattering medium
title_fullStr Exploiting volumetric wave correlation for enhanced depth imaging in scattering medium
title_full_unstemmed Exploiting volumetric wave correlation for enhanced depth imaging in scattering medium
title_short Exploiting volumetric wave correlation for enhanced depth imaging in scattering medium
title_sort exploiting volumetric wave correlation for enhanced depth imaging in scattering medium
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073116/
https://www.ncbi.nlm.nih.gov/pubmed/37015941
http://dx.doi.org/10.1038/s41467-023-37467-z
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